Ongoing projects
AUTOCAST Automatics Cancer Screening Based on Real-time PCR Technology
The future of cervical cancer screening
Cancer accounts for nearly one-quarter of deaths in the developed world, exceeded only by heart diseases. One of the key strategies in cancer prevention is early diagnosis through cancer screening programs. Estimates of premature deaths that could be avoided through cancer screening vary from 3% to 35%, depending on a variety of assumptions. Beyond the potential to reduce mortality, screening may reduce cancer morbidity, since treatment for earlier-stage cancers is often less aggressive than that for more advanced-stage disease. Currently many cancer screening programs, have issues in relation to false negative/ positive results, long time delays in obtaining results and delays in starting treatment.
In this project, we will develop a novel low cost automated real time PCR/probe technology, in a microarray biochip format with corresponding automated detection instrumentation for use as a rapid “point of care” diagnostic device in both a clinical and laboratory setting.
Please visit the official AUTOCAST website!
Jedlik – developing novel biomarker test to indicate cervical cancer
Primary HPV screening is an emerging concept, which may fundamentally influence cervical cancer screening, making impossible to establish new high-throughput automated screening methods in primary screening. Following this path, the combination of HPV testing with screening biomarkers could be the next major milestone. With the advent of a fully automated, low cost, biochemical screening method both the overall quality of the cervical screening programs could be improved and also the programs could be more accessible for women, especially in low resource countries.
During the study a new gene expression, HPV combination panel for cervical screening is being developed.